Neonate with Microphthalmia, Cleft Lip and Palate, Omphalocele, Polydactyly, Atrial Septal Defect and Patent Ductus Arteriosus: A Likely Case of Patau Syndrome

Authors

  • Safana Abdullah Algutaini Department of Public Health and Epidemiologist, East Carolina University, Greenville, USA
  • Alaa Ammer Sreiwy Department of General Surgeon, Alnoor Hospital, Ibb, Yemen

DOI:

https://doi.org/10.70844/jmhrp.2025.2.1.36

Keywords:

Patau syndrome, Trisomy 13, Congenital anomalies, Cleft lip and palate, Omphalocele, Postaxial polydactyly, Atrial Septal Defect (ASD), Patent Ductus Arteriosus (PDA), Neonatal surgery, Genetic disorders, Chromosomal abnormalities, Craniofacial anomalies, Multidisciplinary care, Neonatal outcomes, Family counseling, Pediatric congenital disorders, Abdominal wall defects, Microphthalmia, Cardiac anomalies, Rural healthcare, Yemen case report

Abstract

This report describes a one-day-old female neonate presenting with multiple congenital anomalies, including bilateral microphthalmia, cleft lip and palate, omphalocele, unilateral polydactyly, Atrial Septal Defect (ASD), and Patent Ductus Arteriosus (PDA). The omphalocele was surgically repaired shortly after birth. These features are characteristic of Patau syndrome (Trisomy 13), a rare chromosomal disorder caused by an extra copy of chromosome 13. Genetic testing is ongoing to confirm the diagnosis. This case underscores the importance of early recognition, multidisciplinary care, and family counseling for neonates with severe congenital malformations.

Published

2025-02-06

How to Cite

Algutaini, S. A., & Sreiwy , A. A. (2025). Neonate with Microphthalmia, Cleft Lip and Palate, Omphalocele, Polydactyly, Atrial Septal Defect and Patent Ductus Arteriosus: A Likely Case of Patau Syndrome. Journal of Medical Health Research and Psychiatry, 2(1), 1–3. https://doi.org/10.70844/jmhrp.2025.2.1.36